Word has leaked that today’s press conference is about bacteria with DNA that uses arsenic in place of phosphorus in the structure of its DNA. NASA is framing this has having broad implications for the search for extraterrestrial life, but I am wondering about the evolutionary history of such a critter.
Is there an entire parallel evolutionary history, entire groups of species, that have evolved for billions of years to utilize arsenic? Or is this a more relatively modern technique. Because it’s not as Earth-shattering if these guys turn out to be descendants of regular DNA structure critters (I’m at a loss for good terminology here. They’re not arsenic-“based”—they’re still using carbon as far as I know.) The implications on the search for extraterrestrial life is not so great if they still had to evolve under similar circumstances, and this is just a case of regular, store-brand life adapting to toxic environments like Mono Lake. By which I mean, if the conditions were always toxic, it’s possible that these bacteria would have never had a chance to evolve in the first place.
Of course, there’s another option to them having evolved from regular DNA-based life or even in conjunction over millions and billions of years. That is, they’re not earth-based in origin. Alien invaders, living among us! I suspect the early buzz would have an entirely different tone if that were conclusively the case however.
We’ll learn more at the press conference today, I’m sure, and I’m sure they’ve thought through everything I’ve just went over. I look forward to more details. It’s pretty damned exciting stuff, but for me it’s just a confirmation of a general suspicion, which is that if it’s chemically possible and condusive to self-replication, organisms will find a way. The process of evolution is like opening 10,000 doors simultaneously—I suppose it’s inevitable that some of those doors, when not fatally trapped, will lead to some odd places.


















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New blog post: Some Thoughts on Bacteria with Arsenic DNA http://www.jeremiahtolbert.com/2010/12/s…
@jeremiahtolbert Ok, just read the post. Twhirl hadn’t refreshed before I said that.
@JLCoburn oh no, I was just saying, great minds think alike :)
As I recall, there are dozens of enzymes devoted to phosphorylation and dephosphorylation; if they’ve all adapted to arsenation (sp?) and dearseantion, that’s a huge set of really interesting biology, regardless of where they came from.
I’m hoping they’ll announce the DNA sequence relatedness. That’ll help place this bug in relationship to the rest of us.
Absolutely. I don’t mean to detract. I do want to tamp down a little bit of the hyperbole.
It is closely related to the gamma-proteobacteria, so the trait of arsenic utilization is derived rather than ancestral.
Ah, good to know, thanks. I suppose it was a bit pointless to speculate before the press conference.
Here is what I gathered from skimming through the article in Science (see link below). These bacteria normally use phosphor. It’s only when they are grown solely on arsenic that they can incorporate it into their structure. it’s still monumental that we have a life form that can substitute an element that’s part of its DNA. However not as exciting for me as if the bacteria was using arsenic as the natural building blog of its DNA.
http://www.sciencemag.org/content/early/2010/12/01/science.1197258